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Author (up) Mathie, R.T.; Clausen, J. doi  openurl
  Title Veterinary homeopathy: systematic review of medical conditions studied by randomised trials controlled by other than placebo Type Journal Article
  Year 2015 Publication BMC Veterinary Research Abbreviated Journal BMC Vet Res  
  Volume 11 Issue Pages 236  
  Keywords Homeopathy  
  Abstract BACKGROUND: No systematic review has previously been carried out on randomised controlled trials (RCTs) of veterinary homeopathy in which the control group was an intervention other than placebo (OTP). For eligible peer-reviewed RCTs, the objectives of this study were to assess the risk of bias (RoB) and to quantify the effect size of homeopathic intervention compared with an active comparator or with no treatment. METHODS: Our systematic review approach complied fully with the PRISMA 2009 Checklist. Cochrane methods were applied to assess RoB and to derive effect size using standard meta-analysis methods. Based on a thorough and systematic literature search, the following key attributes of the published research were distinguished: individualised homeopathy (n = 1 RCT)/non-individualised homeopathy (n = 19); treatment (n = 14)/prophylaxis (n = 6); active controls (n = 18)/untreated controls (n = 2). The trials were highly diverse, representing 12 different medical conditions in 6 different species. RESULTS: No trial had sufficiently low RoB to be judged as reliable evidence: 16 of the 20 RCTs had high RoB; the remaining four had uncertain RoB in several domains of assessment. For three trials with uncertain RoB and without overt vested interest, it was inconclusive whether homeopathy combined with conventional intervention was more or was less effective than conventional intervention alone for modulation of immune response in calves, or in the prophylaxis of cattle tick or of diarrhoea in piglets. CONCLUSION: Due to the poor reliability of their data, OTP-controlled trials do not currently provide useful insight into the effectiveness of homeopathy in animals.  
  Address British Homeopathic Association, Hahnemann House, 29 Park Street West, Luton, LU1 3BE, UK. rmathie@britishhomeopathic.org. Karl und Veronica Carstens-Stiftung, Am Deimelsberg 36, D-45276, Essen, Germany. j.clausen@carstens-stiftung.de.  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition 2015/09/16  
  ISSN 1746-6148 (Electronic) 1746-6148 (Linking) ISBN Medium  
  Area Expedition Conference  
  Notes AMED, CINAHL, CENTRAL, Embase, HomVetCR, LILACS, PubMed, Science Citation Index, and Scopus searched. Approved yes  
  Call Number UoN @ rachel.dean @ 1387 Serial 2853  
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