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Author (up) Mathie, R.T.; Clausen, J. url  doi
openurl 
  Title Veterinary homeopathy: meta-analysis of randomised placebo-controlled trials Type Journal Article
  Year 2015 Publication Homeopathy : the Journal of the Faculty of Homeopathy Abbreviated Journal Homeopathy  
  Volume 104 Issue 1 Pages 3-8  
  Keywords Animals; Cattle; Dogs; Pigs; Goats; Homeopathy  
  Abstract BACKGROUND: Meta-analysis of randomised controlled trials (RCTs) of veterinary homeopathy has not previously been undertaken. For all medical conditions and species collectively, we tested the hypothesis that the outcome of homeopathic intervention (treatment and/or prophylaxis, individualised and/or non-individualised) is distinguishable from corresponding intervention using placebos. METHODS: All facets of the review, including literature search strategy, study eligibility, data extraction and assessment of risk of bias, were described in an earlier paper. A trial was judged to comprise reliable evidence if its risk of bias was low or was unclear in specific domains of assessment. Effect size was reported as odds ratio (OR). A trial was judged free of vested interest if it was not funded by a homeopathic pharmacy. Meta-analysis was conducted using the random-effects model, with hypothesis-driven sensitivity analysis based on risk of bias. RESULTS: Nine of 15 trials with extractable data displayed high risk of bias; low or unclear risk of bias was attributed to each of the remaining six trials, only two of which comprised reliable evidence without overt vested interest. For all N = 15 trials, pooled OR = 1.69 [95% confidence interval (CI), 1.12 to 2.56]; P = 0.01. For the N = 2 trials with suitably reliable evidence, pooled OR = 2.62 [95% CI, 1.13 to 6.05]; P = 0.02). CONCLUSIONS: Meta-analysis provides some very limited evidence that clinical intervention in animals using homeopathic medicines is distinguishable from corresponding intervention using placebos. The low number and quality of the trials hinders a more decisive conclusion.  
  Address British Homeopathic Association, Hahnemann House, 29 Park Street West, Luton LU1 3BE, UK. Electronic address: rmathie@britishhomeopathic.org. Karl und Veronica Carstens-Stiftung, Am Deimelsberg 36, D-45276 Essen, Germany.  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition 2015/01/13  
  ISSN 1476-4245 (Electronic) 1475-4916 (Linking) ISBN Medium  
  Area Expedition Conference  
  Notes AMED, CINAHL, Cochrane CENTRAL, Embase, Hom-Inform, HomVetCR (Carstens-Stiftung), LILACS, PubMed, Science Citation Index and Scopus searched Approved yes  
  Call Number UoN @ douglas.grindlay @ 1306 Serial 2790  
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